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Project 3DNeuroN

In the project a microelectronic system was developed to three-dimensionally measure neuronal activity and stimulate nerve cells.

In the future, with the novel solution, it should be possible to achieve specific control of the healing of cellular tissues of the central nervous system which have been damaged by trauma or disease.

IMMS together with project partners worked on a new 3-dimensional low-power, low-noise sensor-actuator electrode system. The array is of a tiny (only a few mm3) stack of ten comb-like units containing 800 sensors in total. They are arranged in a tiny space so as to enable any future implants to be kept as compact as possible. In the novel spatial structure, the nerve cells will be able to grow in an almost natural environment, whereas the arrays previously available only supported planar growth. Now, for the first time, the connection between this sensor format and the biological tissue is to be made capacitatively rather than galvanically, to prevent unwanted electrical currents and ensure the bio-compatibility of the array.

IMMS has undertaken the design and production of 3.8 mm wide 80-channel sensor and actuator microchips. They will perform the evaluation of the signals and control of the actuators. Using 10 of these ASICs, it will be possible continuously to receive the signals from all 800 sensors at once, amplifying them at low noise. It will also be possible to stimulate the tissue using extremely low power and thus causing only a minimal rise in temperature to prevent irreversible damage to the nerve cells.

Therefore, IMMS focussed on how to model the biological environment in the form of electrical signals and then on how to connect the evaluation electronics to this environment so that the biological signals might be processed.

Acronym / Name:

3DNeuroN / Development of a new low-power, low-noise 3d multisensor/actuator array system.

Duration:2012 – 2014

Project website:3DNeuroN

Application:

Life Sciences|biosensors| bioactuators| biosignal acquisition| biosignal generation

Research field:Integrated sensor systems


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Contact

Contact

Eric Schäfer, M. Sc.

Head of Microelectronics / Branch Office Erfurt

eric.schaefer(at)imms.de+49 (0) 361 663 25 35

Eric Schäfer and his team research Integrated sensor systems, especially CMOS-based biosensors, ULP sensor systems and AI-based design and test automation. The results are being incorporated into research on the lead applications Sensor systems for in-vitro diagnostics and RFID sensor technology. It will assist you with services for the development of Integrated circuits and with IC design methods.

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Core topic

CMOS-based biosensors

We are researching CMOS-integrated transducers and their interaction with biological receptors. They offer the potential for precise, digital and cost-effective point-of-care tests and allow properties to be recorded on a molecular scale.

Research field

Integrated sensor systems

Here we investigate miniaturised systems manufactured in semiconductor technology consisting of microelectronic components for sensors applications, as well as methods to design these highly complex systems efficiently and safely.

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