Andrea Kulik, FRIZ Biochem
We were particularly impressed by IMMS’s ability to take a holistic approach to the interface between biochemical applications and electronic signal processing. This enabled our biochemical and technical requirements to be precisely translated into microelectronic concepts and implemented in a space-efficient manner.
“We develop innovative molecular diagnostic solutions for standardised (high-throughput) use in the laboratory, as well as for direct point-of-care testing. Our products stand for high sensitivity, short turnaround times and user-friendly workflows.
We have appointed IMMS as our development partner for our CYCLE® Dx platform, which enables rapid, highly sensitive and fully automated multiparametric PCR analyses to be carried out directly at the point of care without the need for a laboratory. The CMOS biochip, developed in collaboration with IMMS to detect DNA hybridisation on electrochemical sensor arrays, will in future be integrated into the analysis unit of our PoC platform.
In previous research projects, we laid the technological foundations and validated the performance of our CMOS biochip approaches. The aim of the subsequent collaboration was to work with IMMS to translate these findings into a commercially viable product. The company’s proven expertise in the development of analog and digital integrated circuits and systems, particularly in the field of CMOS biosensors, was particularly convincing.
The IMMS team contributed extensive expertise in the CMOS technology used, as well as in specialised manufacturing processes, including microsystem techniques for integrating precious-metal electrodes directly onto the chip and TSV technologies for bond-wire-free integration into our analysis unit. The process steps required for this were provided by our long-standing partner X-Fab and seamlessly integrated into the overall system.
We were particularly impressed by IMMS’s ability to take a holistic approach to the interface between biochemical applications and electronic signal processing. This enabled our biochemical and technical requirements to be precisely translated into microelectronic concepts and implemented in a space-efficient manner.
In addition to technological excellence, the collaboration was characterised throughout by agility, transparency and reliability. Coordination was swift and solution-oriented, and all milestones were met on schedule and to a high standard.
We would like to express our sincere thanks for the professional and trustful partnership and look forward to continuing to work together on future innovation projects.“
The reference is related to:
Core topic
CMOS-based biosensors
We are researching CMOS-integrated transducers and their interaction with biological receptors. They offer the potential for precise, digital and cost-effective point-of-care tests and allow properties to be recorded on a molecular scale.
Service for R&D
Integrated Circuits
We offer the design and realisation of application-specific integrated circuits (ASICs) in CMOS, BiCMOS and SOI technologies. We achieve well-performing ASICs with our first runs (first-time right silicon).
Research field
Integrated sensor systems
Here we investigate miniaturised systems manufactured in semiconductor technology consisting of microelectronic components for sensors applications, as well as methods to design these highly complex systems efficiently and safely.
Lead application
Sensor systems for in-vitro diagnostics
Here we are developing sensor systems for in-vitro diagnostics that enable individual, decentralised health monitoring for all with electronic rapid tests.